Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFSF15 O95150 TNF superfamily member 15 Signaling 2.8E-03 0.531 0.692
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR7 Q9NYK1 toll like receptor 7 0.98 0.464 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
SUOX P51687 sulfite oxidase 9.4E-07 0.638 0.615
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
NKD1 Q969G9 NKD inhibitor of WNT signaling pathway 1 0.99 0.621 0.385
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846
LURAP1L Q8IV03 leucine rich adaptor protein 1 like 2.5E-02 0.736 0.269
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
LRBA P50851 LPS responsive beige-like anchor protein 7.2E-12 0.608 0.692
LINC01250 long intergenic non-protein coding RNA 1250 0.743 0.231
LINC00993 long intergenic non-protein coding RNA 993 0.729 0.269
KIR3DL2 P43630 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Receptor 6.1E-12 0.543 0.769